Overview Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group based in Boston's Seaport District. The Health Economics & Outcomes Research Associate Director will participate in the shaping and execution of HEOR strategies that optimize the value proposition for Vertex's Cystic Fibrosis and early pipeline assets through each stage of development, including launch and post-launch phases. This position reports to the Senior Director HEOR, CF and Early Pipeline. Key Duties and Responsibilities Leads execution of complex HEOR evidence generation studies, including: prospective and retrospective observational studies, systematic literature reviews, cost-effective analyses and budget impact models, Indirect Treatment Comparisons, COA strategy, PRO measure development and validation, as needed, to support the asset value Effectively leads external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; is accountable for study design, data analysis and the quality of the evidence produced. Excellent project management is a pre-requisite to ensure studies delivered on time and within budget. Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact Partners and works closely with Global Pricing and Market Access to support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier) Knowledge and Skills Strong track record of publication in peer-reviewed journals Strong background in clinical outcome assessment (COA) measurement strategy; experience in PRO development/validation and qualitative research methodology Technical expertise in HEOR; able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct Education and Experience Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline. Typically requires 8 years of experience, with substantial background in HEOR, or the equivalent combination of education and experience Pay Range $172,000 - $258,000 Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status In this Hybrid-Eligible role, you can choose to be designated as:
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